If your pet has a reaction after receiving a medication, it is important to report it. Reporting side effects helps veterinarians, drug companies, and safety agencies better understand how medicines work in real life and how to keep pets safe.
This is especially important for newer arthritis medications like Librela and Solensia.
What Are Librela and Solensia?
Librela is an injectable arthritis medication used in dogs. Its generic name is bedinvetmab. In Australia, this same medication is called Beransa.
Solensia is an injectable arthritis medication used in cats. Its generic name is frunevetmab.
Both medications work by blocking nerve growth factor (NGF), a protein involved in pain signaling. By blocking NGF, these drugs can help reduce arthritis pain and improve comfort.
A Note About Anti-NGF Pain Medicines
Anti-NGF medicines are newer drugs used to help dogs and cats with chronic pain, like arthritis. These treatments reduce pain by blocking nerve growth factor, which sends pain signals in the body. They are often given as injections and are used when other pain medicines aren’t enough.
Like all medicines, anti-NGF drugs can have side effects. Most reported side effects from anti-NGF medicines are mild or moderate, such as temporary tiredness, mild soreness at the injection site, or slight changes in movement. Serious side effects with these drugs are uncommon, but veterinarians watch carefully and ask owners to report what they see so they can make good decisions about treatment.
What Is a Side Effect?
A side effect, also called an adverse event, (here is a link to my post about those to learn more: https://drbrunke.blog/2026/02/10/understanding-medicine-side-effects-for-pets/) is any unwanted change that happens after your pet receives a medication. This can include mild changes, such as tiredness, or more serious problems, such as trouble walking or needing hospital care.
You do not need to be sure that Librela or Solensia caused the problem to report it. If something unusual happens after an injection, it is okay, and encouraged, to report it.
Why Reporting Side Effects Matters
Zoetis, the company that makes Librela and Solensia, and government safety agencies ask veterinarians and pet owners to report all possible side effects. This helps experts look for patterns, weigh benefits and risks, and update safety information over time.
Reporting is not about blaming anyone. It is about sharing information so pets can be treated as safely as possible.
Who Can Report a Side Effect?
Both veterinarians and pet owners can report side effects related to bedinvetmab or frunevetmab. If you notice a change in your dog or cat after an injection, talk with your veterinarian and consider reporting it.
What Information Is Helpful to Report?
When reporting a possible side effect from Librela or Solensia, it helps to include:
• your pet’s age, breed, and weight
• which medication was given (Librela/bedinvetmab or Solensia/frunevetmab)
• when the medication was started and when the last dose was given
• what signs or changes you noticed
• how soon the signs started after the injection
• whether your pet recovered, is still affected, or became worse
Veterinarians use specific adverse event report forms for Librela and Solensia to collect this information.
Report Side Effects to BOTH Zoetis and the Government
It is important to report side effects separately to two places:
- Zoetis (the manufacturer)
- Your country’s government safety agency
Reporting to only one is not enough. Each group tracks safety information in different systems, and both need to receive the report.
How to Report Side Effects to Zoetis
Side effects for bedinvetmab (Librela/Beransa) or frunevetmab (Solensia) should be reported directly to Zoetis.
It is best to call or email Zoetis rather than using an online form. Calling or emailing gives you a reference number, which allows the report to be tracked. Online forms usually do not give a tracking number.
In the United States, call Zoetis at 1-888-Zoetis1 (1-888-963-8471).
In the UK or Europe, call 0345 300 8034 or email customersupportUK@zoetis.com.
For other countries, Zoetis provides local contact numbers by region.
Always ask for a reference number when you report.
How to Report Side Effects to Government Safety Agencies
Side effects should also be reported directly to your country’s government safety authority. This step is separate from reporting to Zoetis and should be done even if Zoetis has already been contacted.
Examples include:
• United States: FDA MedWatch
• United Kingdom: Veterinary Medicines Directorate
• Europe: National medicines agencies
• Canada: Health Canada
• Australia: Therapeutic Goods Administration
ANYONE from around the globe can report adverse events if it’s from a veterinary drug approved by the FDA.
You can Google the form, search for “1932a form” or open this link: https://www.fda.gov/media/121602/download
Your veterinarian can help you find the correct reporting site if you are unsure.
What Pet Owners Should Remember
Most pets tolerate Librela and Solensia well, but no medication is risk-free. If something does not seem right after your pet receives bedinvetmab or frunevetmab, speak up.
You do not need proof. You do not need to be certain. Reporting concerns to both Zoetis and your government safety agency helps protect your pet and other pets.
If you are unsure how to report a side effect, your veterinarian can help guide you through the process.
Here is a link to more information and the forms to report a potential adverse event
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